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Simultaneous use of benzodiazepines and opioids may well cause respiratory melancholy, profound sedation, coma, and Dying—Reserve concomitant prescribing of these drugs for sufferers with inadequate different treatment solutions. Limit dose towards the minimal to reduce lethal respiratory despair.[26]
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In addition to their handy effects, most medicines may cause undesired side-effects although not Everybody activities them. The desk under incorporates some of the commonest kinds related to dihydrocodeine.
Propylene glycol toxicity is actually a here scarce toxidrome linked to the parenteral utilization of diazepam. Propylene glycol is a typical diluent used in the suspension of IV diazepam. Large doses or where can i buy cocodamol long-phrase infusions of IV diazepam can result in accumulation of propylene glycol and subsequent anion hole metabolic acidosis.
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